Molecular biologist Prof Jacob Corn describes how gene editing is carried out with CRISPR-Cas9. He explains why this technology has the potential of revolutionizing the treatment of diseases such as sickle cell anemia and malaria. Besides human health, CRISPR-Cas9 can also contribute to improving agriculture and, consequently, food security. Jacob also discusses the possible ethical challenges posed by the widespread application of gene editing. Presented by Dr Andi Horvath.
Virologist Eddie Holmes explains how viral and bacterial pandemics of the type that spawned the Black Death and Ebola remain an unpredictable and inevitable part of our future. Professor Holmes describes how new technologies like genomic sequencing help us explore the origins and evolution of pathogens linked to pandemics as far back as Ancient Rome, and how evolving biosecurity and surveillance systems offer us a chance of containing outbreaks. Presented by Dr Andi Horvath.
In our annual PhD episode, we chat with two young researchers on their diverse investigations. We hear from bioscientist Anne Aulsebrook, who is looking at how urban lighting and light pollution is impacting the health and behaviour of wild birds that make their home in our cities. We also speak to chemical engineer Mitchell Nothling about his research into how enzymes like those found in our digestive systems could be harnessed to create sustainable and more efficient detergents. Presented by Dr Andi Horvath.
Virologist and infectious diseases expert Prof John Fazakerley details the myriad threats to the global food supply from pathogen infestations in crops and livestock, and how new genetic and surveillance technologies are lending hope to keeping them in check. Presented by Dr Andi Horvath.
Renowned paleoanthropologist Bernard Wood explains how continuing research into fossil and other evidence of our evolutionary history produces insights but also reveals how much we have yet to learn. How good, for example, are we at telling our recent ancestors and close relatives from those of the apes? How can we know how many species preceded our own? And can we tell which of those species are our ancestors, and which are non-ancestral close relatives? Presented by Dr Andi Horvath.
Evolutionary biologist and historian of science Prof Lee Dugatkin joins Dr Andi Horvath to discuss displays of altruism in insects, animals and humans, and how the often harsh evolutionary imperatives of survival can actually accommodate, promote or depend on acts of kindness and justice.
Decision science researcher Prof Peter Bossaerts argues that investigating brain activity as we make decisions is generating new insights into how we deal with uncertainty and risk. Once the domain of economists and psychologists, the study of human decision-making is increasingly taking a neuron-level view, with implications well beyond economics and finance. Presented by Eric van Bemmel.
Behavioral neuroscientist Prof Andrew Lawrence joins host Dr Andi Horvath to discuss addictive and compulsive behaviors around drug and alcohol use, the power of psychological dependence, and how the brains of addicts differ from those of the rest of us.
In our annual PhD episode, two young science researchers discuss their investigations of microbes that threaten, respectively, human health and our food supply. We chat with Claire Gorrie about aspects of the drug-resistant bacterium Klebsiella pneumoniae, and how it's implicated in serious infections. And Rebecca Vandegeer tells us how the Barley Yellow Dwarf virus strips our wheat crops of their defences, posing a threat to food security. Presented by Dr Andi Horvath.
Bioethicist Peter Sandøe discusses our complicated relationship with animals and associated moral dilemmas, including how our love for companion animals can actually cause harm and the difference between society’s treatment of pets and production animals. Presented by Peter Clarke.